[Antibody mediated adherence of rat peritoneal exudate cells to Trichinella spiralis larvae]. 1977

A Perrudet-Badoux, and R A Binaghi

Washed peritoneal exudate cells from rats firmly adhere to Trichinella spiralis larvae in the presence of serum containing anti-Trichinella antibodies. This effect is observed when muscle larvae, cells and dilutions of antisera are incubated for 1 h at 37 degrees C.. No adherence takes place at 4 degrees. Whole serum or its gammaglobulin fraction are active and the effect is inhibited by the addition of Trichinella antigens. Complement is not essential since antiserum heated for 2 h at 56 degrees is active. Washed cells from infested animals do not adhere to the larvae in the absence of antiserum, but normal cells adhere to larvae previously incubated with antisera. It is suggested that the adherence phenomenon is due to the activation of cells by a complex of antigen and antibody formed on the surface of the larvae.

UI MeSH Term Description Entries
D007814 Larva Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals. Maggots,Tadpoles,Larvae,Maggot,Tadpole
D002448 Cell Adhesion Adherence of cells to surfaces or to other cells. Adhesion, Cell,Adhesions, Cell,Cell Adhesions
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000906 Antibodies Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
D001202 Ascitic Fluid The serous fluid of ASCITES, the accumulation of fluids in the PERITONEAL CAVITY. Peritoneal Effusion,Peritoneal Fluid,Ascitic Fluids,Effusion, Peritoneal,Fluid, Ascitic,Fluid, Peritoneal,Peritoneal Effusions,Peritoneal Fluids
D014234 Trichinella A genus of parasitic nematodes that causes TRICHINELLOSIS in man and other animal. Trichina,Trichinas,Trichinellas
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

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