Biomaterial Database

Hospital screening of coeliac disease in Estonian children by anti-gliadin antibodies of IgA class. 1993

O Uibo, and H I Maaroos

Department of Paediatrics, Tartu University, Estonia.

Seven hundred consecutive patients from Tartu Children's Clinic were screened for coeliac disease by IgA class anti-gliadin antibody enzyme-linked immunosorbent test during January 1 to May 31, 1991. A positive anti-gliadin antibody test result was revealed in 11 children and in 8 coeliac disease was diagnosed according to the criteria of the European Society for Paediatric Gastroenterology and Nutrition. There was no suspicion of coeliac disease before anti-gliadin antibody determinations in five children and two were asymptomatic. In five children, no suspicion of coeliac disease was raised beforehand. The present study shows that coeliac disease is underdiagnosed in Estonia.

UI	MeSH Term	Description	Entries
D007070	Immunoglobulin A	Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions.	IgA,IgA Antibody,IgA1,IgA2,Antibody, IgA
D007223	Infant	A child between 1 and 23 months of age.	Infants
D007413	Intestinal Mucosa	Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.	Intestinal Epithelium,Intestinal Glands,Epithelium, Intestinal,Gland, Intestinal,Glands, Intestinal,Intestinal Gland,Mucosa, Intestinal
D007421	Intestine, Small	The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.	Small Intestine,Intestines, Small,Small Intestines
D008297	Male		Males
D002446	Celiac Disease	A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION.	Gluten Enteropathy,Sprue, Celiac,Sprue, Nontropical,Celiac Sprue,Gluten-Sensitive Enteropathy,Sprue,Disease, Celiac,Enteropathies, Gluten,Enteropathies, Gluten-Sensitive,Enteropathy, Gluten,Enteropathy, Gluten-Sensitive,Gluten Enteropathies,Gluten Sensitive Enteropathy,Gluten-Sensitive Enteropathies,Nontropical Sprue
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D004957	Estonia	A country in Eastern Europe, bordering the Baltic Sea and Gulf of Finland, between Latvia and Russia. The capital is Tallinn.
D005260	Female		Females