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Application of a programmable calculator in data fitting according to one and two compartment open models in clinical pharmacokinetics. 1977

S Niazi

The plasma or blood concentration profiles are fitted by single or two compartment open models using log-linear regression analyses. For two compartment models, "feathering" is performed at 95% equilibration time obtained from raw pharmacokinetic data. The equations have been programmed onto a Texas Instrument SR 52 pocket calculator and recorded on 8.5 X 1.7 cm magnetic strips, facilitating drug dosage regimen calculations through individual patient titrations in a clinical setting.

UI MeSH Term Description Entries
D008433 Mathematics The deductive study of shape, quantity, and dependence. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Mathematic
D003201 Computers Programmable electronic devices designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations. Calculators, Programmable,Computer Hardware,Computers, Digital,Hardware, Computer,Calculator, Programmable,Computer,Computer, Digital,Digital Computer,Digital Computers,Programmable Calculator,Programmable Calculators
D001702 Biopharmaceutics The study of the physical and chemical properties of a drug and its dosage form as related to the onset, duration, and intensity of its action. Pharmaceutics,Pharmaceutic

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