BIOMAT Database Logo BIOMAT Database Logo

The conversion of 3-exo-methylencephalosporin to 3-halomethylcephems; a convenient synthesis of 3'-substituted cephalosporins from penicillins. 1977

G A Koppel, and M D Kinnick, and L J Nummy

UI MeSH Term Description Entries
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D008745 Methylation Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed) Methylations
D010406 Penicillins A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065) Antibiotics, Penicillin,Penicillin,Penicillin Antibiotics
D002511 Cephalosporins A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid. Antibiotics, Cephalosporin,Cephalosporanic Acid,Cephalosporin,Cephalosporin Antibiotic,Cephalosporanic Acids,Acid, Cephalosporanic,Acids, Cephalosporanic,Antibiotic, Cephalosporin,Cephalosporin Antibiotics

Related Publications

G A Koppel, and M D Kinnick, and L J Nummy
[Conversion of penicillins into cephalosporins].
March 1972, Helvetica chimica acta,
G A Koppel, and M D Kinnick, and L J Nummy
Synthesis and antimicrobial properties of substituted beta-aminoxypropionyl penicillins and cephalosporins.
June 1989, Journal of medicinal chemistry,
G A Koppel, and M D Kinnick, and L J Nummy
Syntheses of guanidino-substituted penicillins and cephalosporins.
September 1965, Nature,
G A Koppel, and M D Kinnick, and L J Nummy
Structure--activity relationships in cephalosporins prepared from penicillins. 2. Analogues of cephalexin substituted in the 3-methyl group.
August 1977, Journal of medicinal chemistry,
G A Koppel, and M D Kinnick, and L J Nummy
Synthesis of cephalosporins and penicillins by enzymatic acylation.
December 1977, The Japanese journal of antibiotics,
G A Koppel, and M D Kinnick, and L J Nummy
[Synthesis of 7-(4,7-di-substituted coumarin-3-acetamido)cephalosporins].
January 1989, Yao xue xue bao = Acta pharmaceutica Sinica,
G A Koppel, and M D Kinnick, and L J Nummy
Letter: Stereospecific synthesis of penicillins. Conversion from a peptide precursor.
May 1976, Journal of the American Chemical Society,
G A Koppel, and M D Kinnick, and L J Nummy
Resistance to penicillins and cephalosporins.
January 1965, Antimicrobial agents and chemotherapy,
G A Koppel, and M D Kinnick, and L J Nummy
Penicillins and cephalosporins from isothiazolylacetic acids.
January 1968, Journal of medicinal chemistry,
G A Koppel, and M D Kinnick, and L J Nummy
A convenient preparation of 3-substituted furans: synthesis of perillene and dendrolasin.
April 2002, Organic letters,
Copied contents to your clipboard!