We studied the clinical course, microbiological investigations and laboratory parameters in 10 patients with reactive arthritis (ReA). The number of patients with arthritis included was 10. Triggering agents were: seven patients had positive agglutinating antibody against Yersinia enterocolitica. Three cases had positive antibody test against Chlamydia trachomatis. In all patients antibody test were recovered. The clinical finding were: 4 patients with polyarthritis, 4 mono-oligoarthritis and two cases sacroileitis. The mean of index active joints were 6 (1-14). More frequent pattern were episodes of arthritis with lower limbs joints involvement. Outcome were of 12.1 (2-24) months. All of culture were negative. The laboratory parameters were unremarkable, except ESR were higher, HLA B-27 were positive in 70% of patients. The radiological signs and synovial biopsy studies were not conclusive. Eight patients were treated with antibiotics, not did antibiotics affect over duration of ReA.