-transparent.png){kind=logo}
We characterized the electrophysiological properties of calcium channels in cultured rat hippocampal neurones using omega-agatoxin-TK (omega-Aga-TK) and compared them with those of the P-type channel and the BI (alpha 1A) channel which resembles the Q-type channel. Two types of omega-Aga-TK-sensitive calcium channels were detected in hippocampal neurones. The first type showed slow inactivation, high sensitivity to omega-Aga-TK and low reversibility from omega-Aga-TK-induced block, resembling the P-type channel. The second type showed fast inactivation, low sensitivity to omega-Aga-TK and high reversibility from omega-Aga-TK-induced block. These results suggest that the second type of calcium channel (Q-type-like) plays a prominent role in the hippocampal synaptic transmission.
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
December 1993,
FEBS letters,
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
December 1995,
The Journal of physiology,
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
February 1987,
Science (New York, N.Y.),
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
September 1997,
Pflugers Archiv : European journal of physiology,
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
May 1990,
The Journal of physiology,
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
September 1996,
European journal of pharmacology,
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
April 1995,
The Journal of pharmacology and experimental therapeutics,
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
January 1991,
The Journal of neuroscience : the official journal of the Society for Neuroscience,
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
July 1995,
Proceedings of the National Academy of Sciences of the United States of America,
T Teramoto, and
T Niidome, and
T Miyagawa, and
Y Nishizawa, and
K Katayama, and
K Sawada
September 1997,
British journal of pharmacology,
