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Renal damage in rat hemorrhagic shock model was assessed by estimation of the reactive oxygen metabolites generation (malondialdehyde measured as thiobarbituric acid reactive substances) and antioxidative potential (activity of Cu-, Zn- superoxide dismutase, activity of glutathione reductase and level of sulfhydryl compounds). It was found that treatment with BN 52021 (a platelet-activating factor antagonist), and polyelektrolyte solution had had a beneficial effect in comparison with both the untreated shock and shock treated by reperfusion only.
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Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
