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The effect of cardiopulmonary bypass (CPB) on the cardiopulmonary function after open heart surgery was evaluated by multiple regression analysis in relation with preoperative factors. In cases without decompensated heart failure, the depression of cardiac function and its recovery after CPB were mostly related to cross-clamp time. The pulmonary oxygenation was affected with operation time, and the duration of artificial ventilation correlated with CPB time. From these results, we conclude that CPB is the most important factor determining the cardiopulmonary function after CPB.
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