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The peroxisome is a ubiquitous, subcellular organelle containing more than 50 matrix enzymes that participate in a diverse array of metabolic pathways. Failure to assemble normal peroxisomes is the cellular hallmark of Zellweger syndrome and other human disorders of peroxisome biogenesis. Identification of the genes required for peroxisome biogenesis is proceeding at a rapid pace helped immeasurably by work in other species, particularly various yeasts. The ultimate goals of this effort are to identify all of these genes and to understand how their protein products interact to produce normal appearing and functioning peroxisomes. Attainment of these goals will lead to a better understanding of the peroxisome biogenesis disorders, their pathophysiology and treatment.
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
June 2000,
FEBS letters,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
January 2020,
Advances in experimental medicine and biology,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
November 2016,
Translational science of rare diseases,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
January 2003,
Annual review of genomics and human genetics,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
January 2016,
Proceedings of the Japan Academy. Series B, Physical and biological sciences,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
June 2003,
Seikagaku. The Journal of Japanese Biochemical Society,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
April 2000,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
May 2004,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
January 2000,
Cell biochemistry and biophysics,
N Braverman, and
G Dodt, and
S J Gould, and
D Valle
September 2000,
Expert opinion on investigational drugs,
