Biomaterial Database

Norethisterone enantate in the treatment of premenstrual syndrome. 1995

K D Gunston

Department of Obstetrics and Gynaecology, University of Cape Town.

The aim of this prospective study was to assess whether norethisterone enantate can be recommended for use in patients with premenstrual syndrome (PMS) who also require effective contraception. The subjects were 20 patients with severe PMS who required effective contraception. Premenstrual symptom scores on norethisterone enantate and oral contraceptives were compared. Significantly fewer and less severe symptoms were experienced by patients on norethisterone enantate than those on oral contraceptives. Norethisterone enantate can therefore be recommended for use in patients with PMS who also require effective contraception.

UI	MeSH Term	Description	Entries
D009640	Norethindrone	A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for CONTRACEPTION.	19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)-,Ethinylnortestosterone,Norethisterone,Norpregneninolone,Conceplan,Micronor,Monogest,Nor-QD,Norcolut,Norcolute,Norethindrone, (1 beta)-Isomer,Norlutin,Nor QD,NorQD
D011293	Premenstrual Syndrome	A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.	Premenstrual Tension,Premenstrual Syndromes,Premenstrual Tensions,Syndrome, Premenstrual,Syndromes, Premenstrual,Tension, Premenstrual,Tensions, Premenstrual
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D003277	Contraceptives, Oral, Combined	Fixed drug combinations administered orally for contraceptive purposes.	Combined Oral Contraceptive,Contraceptive Agents, Female, Combined,Oral Contraceptives, Combined,Combined Oral Contraceptives,Contraceptive, Combined Oral,Contraceptives, Combined Oral,Oral Contraceptive, Combined
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man