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Lactate dehydrogenase (L-lactate : NAD+ oxidoreductase, EC 1.1.1.27) activity has been measured on the subpopulations of platelets obtained from blood of diabetic patients. Small, but not large platelets show a lactate dehydrogenase activity higher than that of controls. Moreover, a positive statistically significant correlation was found between the activity of small platelets and the percent of glycated haemoglobin, while no correlation was obtained in the case of large platelets. Since we previously demonstrated that lactate dehydrogenase activity of small platelets is exceedingly high in some clinical and experimental conditions, our results not only confirm the involvement of platelets in diabetes but provide more evidence in support of our previous hypothesis of a relationship between lactate dehydrogenase and in-vivo platelet activation.
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
January 1977,
Problemy endokrinologii,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
January 1985,
Clinical chemistry,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
January 1976,
Voprosy meditsinskoi khimii,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
December 1989,
Clinical chemistry,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
October 1968,
Schweizerische medizinische Wochenschrift,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
September 2023,
Journal of diabetes,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
August 1967,
Journal of biochemistry,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
July 2015,
Prostaglandins & other lipid mediators,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
December 1977,
The New England journal of medicine,
B Zappacosta, and
P De Sole, and
C Rossi, and
G Marra, and
G Ghirlanda, and
B Giardina
September 1984,
The New England journal of medicine,
