Biomaterial Database

Cryptococcal meningitis and confusional psychosis. A case report and literature review. 1995

M A Sa'adah, and G F Araj, and S M Diab, and M Nazzal

Medical Department, Islamic Hospital, Amman, Jordan.

A previously healthy and immuno-competent 22-year-old man presented in confusional psychosis. Cryptococcal meningitis was later found to be the underlying cause as proven by culturing Cryptococcus neoformans serotype A from the cerebrospinal fluid. Combined antifungal therapy with amphotericin B and 5-fluorocytosine resulted in sustained improvement of all mental and physical functions. Cryptococcosis has rarely been reported from the Middle East. This represents the second case from Kuwait.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D003221	Confusion	A mental state characterized by bewilderment, emotional disturbance, lack of clear thinking, and perceptual disorientation.	Confusional State,Bewilderment,Confusion, Post-Ictal,Confusion, Reactive,Disorientation,Confusion, Post Ictal,Confusional States,Post-Ictal Confusion,Reactive Confusion,State, Confusional,States, Confusional
D005437	Flucytosine	A fluorinated cytosine analog that is used as an antifungal agent.	5-Fluorocytosine,Alcobon,Ancobon,Ancotil
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000666	Amphotericin B	Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.	Amphocil,Amphotericin,Amphotericin B Cholesterol Dispersion,Amphotericin B Colloidal Dispersion,Fungizone
D016919	Meningitis, Cryptococcal	Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (From Adams et al., Principles of Neurology, 6th ed, pp721-2)	Cryptococcal Meningitis,Granulomous Cerebral Cryptococcosis,Toruloma,Cerebral Cryptococcosis,Cerebral Cryptococcoses,Cerebral Cryptococcoses, Granulomous,Cerebral Cryptococcosis, Granulomous,Cryptococcal Meningitides,Cryptococcoses, Cerebral,Cryptococcoses, Granulomous Cerebral,Cryptococcosis, Cerebral,Cryptococcosis, Granulomous Cerebral,Granulomous Cerebral Cryptococcoses,Meningitides, Cryptococcal,Torulomas
D019965	Neurocognitive Disorders	Diagnoses of DEMENTIA and AMNESTIC DISORDER are subsumed here. (DSM-5)	Clerambault Syndrome,Delirium, Dementia, Amnestic, Cognitive Disorders,Kandinsky Syndrome,Mental Disorders, Organic,Organic Brain Syndrome, Nonpsychotic,Organic Mental Disorders,Organic Mental Disorders, Psychotic,Psychoses, Traumatic,Mild Neurocognitive Disorder,Nonpsychotic Organic Brain Syndrome,Disorder, Mild Neurocognitive,Disorder, Neurocognitive,Disorders, Mild Neurocognitive,Disorders, Neurocognitive,Disorders, Organic Mental,Mental Disorder, Organic,Mild Neurocognitive Disorders,Neurocognitive Disorder,Neurocognitive Disorder, Mild,Neurocognitive Disorders, Mild,Organic Mental Disorder,Traumatic Psychoses