Treatment for hyperemesis gravidarum in the home: an alternative to hospitalization. 1995

R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson 39216-4505, USA.

Our objective was to determine whether medical therapy in the home for patients with hyperemesis gravidarum is safe, efficacious, and cost effective compared with hospitalization. In this retrospective, matched control study 50 women with hyperemesis were treated in the home and were matched for gravidity, gestational age, and weight loss from prepregnancy weight with 47 patients who were hospitalized for traditional treatment. Both groups had similar intravenous fluid and medical support until they could tolerate adequate oral intake. Women in the home had 9.7 +/- 8.0 days of intravenous therapy compared with 9.5 +/- 6.2 days in hospitalized patients (not significant). The mean percent of weight loss at initiation of therapy was similar in both groups (4.6% +/- 5.7% vs 4.5% +/- 6.1%, not significant). The mean weight change during therapy in the home group was + 1.0 +/- 4.3 pounds compared with +1.2 +/- 8.6 pounds in the hospitalized group (not significant). The only complication was infiltration of the intravenous site, the occurrence of which was similar in the two groups (40% vs 57%, not significant). At discontinuation of therapy 90% of the home patients no longer required any supportive therapy; 10% (n = 5) required hospitalization because of relapse. The cost of therapy was significantly lower for patients in the home group ($708 +/- $533 vs $2701 +/- $1717, p < 0.001). These data show that management of hyperemesis in the home is both safe and efficacious. Furthermore, successful therapy can be achieved in the home at a significantly reduced cost.

UI MeSH Term Description Entries
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D003131 Combined Modality Therapy The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used. Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D003365 Costs and Cost Analysis Absolute, comparative, or differential costs pertaining to services, institutions, resources, etc., or the analysis and study of these costs. Affordability,Analysis, Cost,Cost,Cost Analysis,Cost Comparison,Cost Measures,Cost-Minimization Analysis,Costs and Cost Analyses,Costs, Cost Analysis,Pricing,Affordabilities,Analyses, Cost,Analyses, Cost-Minimization,Analysis, Cost-Minimization,Comparison, Cost,Comparisons, Cost,Cost Analyses,Cost Comparisons,Cost Measure,Cost Minimization Analysis,Cost, Cost Analysis,Cost-Minimization Analyses,Costs,Measure, Cost,Measures, Cost
D004035 Diet Therapy Adjusting the quantity and quality of food intake to improve health status of an individual. This term does not include the methods of food intake (NUTRITIONAL SUPPORT). Diet Therapy, Restrictive,Dietary Modification,Dietary Restriction,Restriction Diet Therapies,Restriction Diet Therapy,Restrictive Diet Therapies,Restrictive Diet Therapy,Diet Modification,Therapy, Diet,Diet Modifications,Diet Therapies,Diet Therapies, Restriction,Diet Therapy, Restriction,Dietary Modifications,Dietary Restrictions,Modification, Diet,Modification, Dietary,Restriction, Dietary,Therapy, Restriction Diet,Therapy, Restrictive Diet
D005260 Female Females
D005440 Fluid Therapy Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to WATER-ELECTROLYTE BALANCE. Fluids may be administered intravenously, orally, by intermittent gavage, or by HYPODERMOCLYSIS. Oral Rehydration Therapy,Rehydration,Rehydration, Oral,Oral Rehydration,Rehydration Therapy, Oral,Therapy, Fluid,Therapy, Oral Rehydration,Fluid Therapies,Oral Rehydration Therapies,Oral Rehydrations,Rehydration Therapies, Oral,Rehydrations,Rehydrations, Oral,Therapies, Fluid,Therapies, Oral Rehydration
D006699 Home Care Services Community health and NURSING SERVICES providing coordinated multiple services to the patient at the patient's homes. These home-care services are provided by a visiting nurse, home health agencies, HOSPITALS, or organized community groups using professional staff for care delivery. It differs from HOME NURSING which is provided by non-professionals. Domiciliary Care,Home Health Care,Care Services, Home,Home Care,Services, Home Care,Care, Domiciliary,Care, Home,Home Care Service,Service, Home Care
D006760 Hospitalization The confinement of a patient in a hospital. Hospitalizations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006939 Hyperemesis Gravidarum Intractable VOMITING that develops in early PREGNANCY and persists. This can lead to DEHYDRATION and WEIGHT LOSS. Pernicious Vomiting of Pregnancy,Pregnancy Pernicious Vomiting

Related Publications

R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
July 1998, Primary care update for Ob/Gyns,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
September 2000, Journal of perinatology : official journal of the California Perinatal Association,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
August 1996, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
June 2017, Archives of women's mental health,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
January 2012, Midwives,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
September 1922, California state journal of medicine,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
October 1957, Medizinische Klinik,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
December 1982, Nihon Sanka Fujinka Gakkai zasshi,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
April 1947, Canadian Medical Association journal,
R W Naef, and S P Chauhan, and H Roach, and W E Roberts, and K H Travis, and J C Morrison
January 1953, Medicamenta,
Copied contents to your clipboard!