Total artificial heart: from bridge to transplantation to permanent use. 1996

W S Pierce, and J S Sapirstein, and W E Pae
Department of Surgery, Pennsylvania State University, College of Medicine, Milton S. Hershey Medical Center, Hershey 17033-0850, USA.

BACKGROUND Pneumatic artificial hearts have played an important role in supporting the circulation in patients before cardiac transplantation. Pneumatic hearts have also been used for permanent cardiac replacement, but most agree they have serious limitations. METHODS Several groups are now developing electric artificial hearts in which electrical energy crosses the skin using a wireless technique. The electrical energy powers a small direct-current motor, which actuates the blood pump. RESULTS Important progress in these devices has resulted in animal survival with electric hearts of more than 1 year. CONCLUSIONS Extensive bench testing and animal testing will be performed before the initial clinical use of these devices will be initiated. One of the early scientific achievements of the 21st century will be the initial use of the electric artificial heart in humans.

UI MeSH Term Description Entries
D004867 Equipment Design Methods and patterns of fabricating machines and related hardware. Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D006354 Heart, Artificial A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (Dorland, 28th ed) Artificial Heart,Artificial Hearts,Hearts, Artificial
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D016027 Heart Transplantation The transference of a heart from one human or animal to another. Cardiac Transplantation,Grafting, Heart,Transplantation, Cardiac,Transplantation, Heart,Cardiac Transplantations,Graftings, Heart,Heart Grafting,Heart Graftings,Heart Transplantations,Transplantations, Cardiac,Transplantations, Heart

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