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Pregnancy limits the therapeutic options for managing thrombocytopenia which occurs in 5% of patients on heparin. We describe a case of extensive thromboembolism associated with antithrombin (AT) deficiency complicated by thrombocytopenia which resolved when low-molecular-weight heparin was instituted. A primigravid woman presented at 11 weeks gestation with bilateral femoral occlusive thrombi extending above the renal veins. Investigations revealed AT deficiency, thrombocytopenia and renal infarction. After low-molecular-weight heparin was substituted for unfractionated heparin, the thrombocytopenia resolved and although the pregnancy was lost, the patient made a full recovery.
N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
January 2000,
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology,
N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
August 2000,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
March 1999,
Lancet (London, England),
N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
January 2010,
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N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
February 1986,
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N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
January 1987,
Geburtshilfe und Frauenheilkunde,
N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
January 1988,
La Revue de medecine interne,
N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
January 1995,
Journal of thrombosis and thrombolysis,
N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
October 1995,
Anales de medicina interna (Madrid, Spain : 1984),
N S Macklon, and
I A Greer, and
A W Reid, and
I D Walker
January 1994,
Progress in cardiovascular diseases,
