Effect of interstimulus interval on evoked otoacoustic emissions. 1995

G Lina-Granade, and L Collet
Département d'Oto-Rhino-Laryngologie, URA CNRS 1447, Université Claude Bernard, Hôpital E. Herriot, Lyon, France.

In order to explore extensively the effect of interstimulus interval, including very short interstimulus intervals, on evoked otoacoustic emissions (EOAEs), several EOAE recordings were carried out using pairs of clicks: a suppressor click preceded the stimulus click generating an EOAE, with various intervals between the two clicks. EOAEs elicited by two clicks separated by intervals under 8-9 ms had significantly smaller amplitudes than EOAEs evoked by the stimulus alone. The amplitude decay correlated with the interclick interval, and was about 40% when the interclick interval decreased from 12 to 1 ms. This phenomenon has been noted before but not precisely quantified. It might reflect an adaptive mechanism within the outer hair cells, which has been previously described, or else mechanical interactions on the basilar membrane. The delay in EOAE decrease is of the same order as the first phase of neural adaptation, known as 'rapid adaptation', and these thus may prove to be correlated.

UI MeSH Term Description Entries
D008297 Male Males
D003051 Cochlea The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH. Cochleas
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000704 Analysis of Variance A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses
D017084 Otoacoustic Emissions, Spontaneous Self-generated faint acoustic signals from the inner ear (COCHLEA) without external stimulation. These faint signals can be recorded in the EAR CANAL and are indications of active OUTER AUDITORY HAIR CELLS. Spontaneous otoacoustic emissions are found in all classes of land vertebrates. Spontaneous Otoacoustic Emissions,Otoacoustic Emission, Spontaneous,Spontaneous Otoacoustic Emission
D018072 Hair Cells, Auditory, Outer Sensory cells of organ of Corti. In mammals, they are usually arranged in three or four rows, and away from the core of spongy bone (the modiolus), lateral to the INNER AUDITORY HAIR CELLS and other supporting structures. Their cell bodies and STEREOCILIA increase in length from the cochlear base toward the apex and laterally across the rows, allowing differential responses to various frequencies of sound. Auditory Hair Cell, Outer,Auditory Hair Cells, Outer,Cochlear Outer Hair Cell,Cochlear Outer Hair Cells,Hair Cell, Auditory, Outer,Hair Cells, Auditory, Outer Inner,Outer Auditory Hair Cell,Outer Auditory Hair Cells,Outer Hair Cells,Hair Cells, Outer

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