Recently, computer systems including several delivery systems have been installed in the Central Clinical Laboratory of Kyoto University Hospital. As for the physiological examination system, we have introduced PRINS (Physiological-examination Result Information Network System) using an NEC computer and LAN. Utilizing Windows, this PRINS is connected to individual systems and equipment, and the data are sent to the host computer system (KING: Kyoto University Hospital Information Network Galaxy, which utilizes IBM). This system enabled us to greatly improve (1) the efficacy of examinations, (2) management and data-stock of huge volumes, (3) rapid data analyses and simplicity in handling, and (4) facility of reception and reservation business. As for the sample analysis system, we formerly developed computer systems using MUMPS independently in the subdivisions. At the time of delivery system installation, we decided to unify them and newly establish a general managing system using MUMPS Sumitomo Electric Industries. The purpose of these installations are briefly as follows; (1) to reduce human power and to simplify delivery of samples and related business, (2) to report the assay results rapidly, (3) to improve and automate the quality controls, (4) to prevent from infections, and (5) to make handling and work easier. This system is comprised of biochemistry, immunology, hematology and emergency examination subdivisions, and connects each part in a network system using LAN. This is further connected to KING, the host. Actually, 4 sample delivery lines from 3 industries were introduced: Hitachi for biochemistry, Sysmex for hematology, and Toshiba-IDS for coagulation and immunology. Monitoring and data analyses including quality controls are performed by a host system or individual systems (biochemistry and hematology). At present, such heterogeneous installations were considered to be most suitable for our purpose and these made it possible to continue assays of other lines even when trouble occurred in one of the lines. In addition to the general systems, we have introduced various software programs for statistical analyses. These have been effectively utilized already for detailed setting of the clinical reference values for hematology data, and also for a computer diagnosis trial for anemia related diseases. When effective operations of these newly installed systems is achieved, we would like to extend our efforts to establish an ideal laboratory which is able to assist the intensive medi-care system in the university hospital.