-transparent.png){kind=logo}
The combination of radiotherapy and thermotherapy has the greatest antitumor effect when delivered simultaneously. We developed and have clinically used an applicator that enables simultaneous intraluminal irradiation and hyperthermia delivery for the treatment of locally invasive esophageal carcinoma. In a phase 1 study, 40 Gy of external irradiation was delivered followed by simultaneous intraluminal hyperthermia and radiotherapy once weekly for three weeks. Intraluminal hyperthermia was delivered to the mucosal surface at 42 to 44 degrees C for 30 minutes. Intraluminal irradiation (3 Gy) was delivered to a submucosal depth of 5 mm after the first 15 minutes of hyperthermia. This treatment may increase current treatment results for locally invasive esophageal carcinoma, which have otherwise been maximized.
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
April 1986,
Gan to kagaku ryoho. Cancer & chemotherapy,
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
June 1985,
Zhonghua bing li xue za zhi = Chinese journal of pathology,
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
June 1992,
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al],
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
January 1995,
Tumori,
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
May 1991,
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al],
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
October 1987,
The Surgical clinics of North America,
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
November 1987,
Cancer treatment reports,
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
January 1985,
Langenbecks Archiv fur Chirurgie,
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
March 1979,
MMW, Munchener medizinische Wochenschrift,
N Fuwa, and
Y Nomoto, and
K Shouji, and
T Nakagawa, and
Y Ito, and
Y Kikuchi
December 1996,
International journal of radiation oncology, biology, physics,
