Biomaterial Database

Preferential and absolute adsorption to poly[N5-(3-hydroxypropyl)-L-glutamine] in water/2-chloroethanol solvent mixtures. 1977

C Feyereisen, and M Morcellet, and C Loucheux

Preferential adsorption to poly[N5-(3-hydroxypropyl)-L-glutamine] (PHPG) in water/2-chloroethanol solvent mixtures has been determined by measuring density increments at constant concentration and at constant chemical potential. At low alcohol concentrations, decreasing preferential adsorption of 2-chloroethanol is observed. When the organic solvent content is increased, an inversion of preferential adsorption occurs, water being preferentially adsorbed. The inversion zone parallels the conformational transition curve. As an explanation it is proposed that a competition occurs between noninteracting helicogenic 2-chloroethanol, which stabilizes hydrophobic interactions, and the hydrophilic interactions of water with PHPG. The former retains a helical structure, whereas the latter induces a helix-to-coil transition.

UI	MeSH Term	Description	Entries
D010455	Peptides	Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS.	Peptide,Polypeptide,Polypeptides
D005023	Ethylene Chlorohydrin	Used as a solvent, in the manufacture of insecticides, and for treating sweet potatoes before planting. May cause nausea, vomiting, pains in head and chest, stupefaction. Irritates mucous membranes and causes kidney and liver degeneration.	2-Chlorethanol,2-Chloroethyl Alcohol,Ethylenechlorhydrin,2 Chlorethanol,2 Chloroethyl Alcohol,Alcohol, 2-Chloroethyl,Chlorohydrin, Ethylene
D005973	Glutamine	A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.	D-Glutamine,L-Glutamine,D Glutamine,L Glutamine
D000327	Adsorption	The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.	Adsorptions
D014867	Water	A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Hydrogen Oxide