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Authors describe a case of chronic aggressive hepatitis with persistent HBs (Australia) antigenaemia and nephrosis syndrome. The renal process microscbically appeared to be membranous glomerulonephritis. By immunofluorescent method antigen deposits IgG, IgM, C3 and HBs of the granular type have been revealed on the glomerular basal membranes. Deposits of the IgA were partially of granular, partially of linear type. Electronmicroscopically on the glomerular basale membrane subepithelial deposits were seen. The results of this study indicate that in the case reported diffuse membranus glomerulonephritis occurred due to HBs antigen-antibody immuno-deposits on the glomerular basal membrane.
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