Biomaterial Database

The object delayed non-matching to sample task in rats does not depend on working memory. 1995

A H Herremans, and T H Hijzen, and J L Slangen

Department of Psychopharmacology, Rudolf Magnus Institute for Neurosciences, Faculty of Pharmacy, Utrecht University, The Netherlands.

Four rats were trained on an object delayed non-matching to sample task to measure working memory (WM). On separate trials a sample object was presented to the rat, which was presented again along with another object after a 3 s delay rats were rewarded with food if they chose the novel object. In this procedure the choice objects are positioned in a fixed order (the novel object was positioned at first, followed by the sample object). When the order of placement of the choice objects was reversed performance dropped from 87% to 28% correct, showing that the rats always chose the object that was first positioned into the choice area. When the order of positioning of the choice objects was randomized during training, rats were not able to learn the task. It is suggested that performance is based on a discrimination between choice objects instead of WM.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008568	Memory	Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
D004192	Discrimination, Psychological	Differential response to different stimuli.	Discrimination, Psychology,Psychological Discrimination
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001522	Behavior, Animal	The observable response an animal makes to any situation.	Autotomy Animal,Animal Behavior,Animal Behaviors
D013647	Task Performance and Analysis	The detailed examination of observable activity or behavior associated with the execution or completion of a required function or unit of work.	Critical Incident Technique,Critical Incident Technic,Task Performance,Task Performance, Analysis,Critical Incident Technics,Critical Incident Techniques,Incident Technic, Critical,Incident Technics, Critical,Incident Technique, Critical,Incident Techniques, Critical,Performance, Analysis Task,Performance, Task,Performances, Analysis Task,Performances, Task,Task Performances,Task Performances, Analysis,Technic, Critical Incident,Technics, Critical Incident,Technique, Critical Incident,Techniques, Critical Incident
D017208	Rats, Wistar	A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.	Wistar Rat,Rat, Wistar,Wistar Rats
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus