Binaural phase effects in the auditory brainstem response. 1995

C G Fowler, and C M Mikami
Veterans Affairs Medical Center, Long Beach, California 90822, USA.

This study investigated the possibility of a correlate of the masking level difference (MLD) in the auditory brainstem response (ABR), given that behavioral data indicate the brainstem origination of the MLD. Previous studies have reported MLD characteristics in the late auditory evoked potentials. In the present study, stimuli were presented in S(o)N(o) and S pi N(o) to female adults with normal hearing. In experiment 1, a binaural phasic difference potential (BPD) was derived by subtracting the suprathreshold ABRs to S(o)N(o) from S pi N(o) for tone pips of 500 to 4000 Hz. The magnitude of the BPD was inversely related to frequency. In experiment 2, thresholds to 500-Hz tone pips in S(o)N(o) and S pi N(o) were equal. In a case study of a subject with no behavioral MLD, the 500-Hz BPD was abnormal on one side, suggesting unilateral interruption of phase synchrony in the brain stem. Thus, the results of this study, in conjunction with previous studies on late potential correlates of the MLD, suggest that the ability to maintain phase information through the brain stem is necessary but not sufficient to generate the MLD.

UI MeSH Term Description Entries
D010470 Perceptual Masking The interference of one perceptual stimulus with another causing a decrease or lessening in perceptual effectiveness. Masking, Perceptual,Maskings, Perceptual,Perceptual Maskings
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001309 Auditory Threshold The audibility limit of discriminating sound intensity and pitch. Auditory Thresholds,Threshold, Auditory,Thresholds, Auditory
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D016057 Evoked Potentials, Auditory, Brain Stem Electrical waves in the CEREBRAL CORTEX generated by BRAIN STEM structures in response to auditory click stimuli. These are found to be abnormal in many patients with CEREBELLOPONTINE ANGLE lesions, MULTIPLE SCLEROSIS, or other DEMYELINATING DISEASES. Acoustic Evoked Brain Stem Potentials,Auditory Brain Stem Evoked Responses,Brain Stem Auditory Evoked Potentials,Evoked Responses, Auditory, Brain Stem,Acoustic Evoked Brain Stem Potential,Acoustic Evoked Brainstem Potential,Acoustic Evoked Brainstem Potentials,Auditory Brain Stem Evoked Response,Auditory Brain Stem Response,Auditory Brain Stem Responses,Auditory Brainstem Evoked Response,Auditory Brainstem Evoked Responses,Auditory Brainstem Responses,Brain Stem Auditory Evoked Potential,Brainstem Auditory Evoked Potential,Brainstem Auditory Evoked Potentials,Evoked Potential, Auditory, Brainstem,Evoked Potentials, Auditory, Brainstem,Evoked Response, Auditory, Brain Stem,Evoked Response, Auditory, Brainstem,Evoked Responses, Auditory, Brainstem,Auditory Brainstem Response,Brainstem Response, Auditory,Brainstem Responses, Auditory,Response, Auditory Brainstem,Responses, Auditory Brainstem

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