The investigation of the non-jaundiced patient by percutaneous transhepatic cholangiography (PTC) and the indications for this examination are presented. Diagnostic examinations were obtained in all 15 patients studied despite the absence of jaundice at the time of examination. Complications were minimal. The value of this method particularly after previous biliary surgery is emphasized. It is suggested that PTC may be of great value, and safely used in non-jaundiced patients.