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OBJECTIVE To demonstrate normal MR anatomy of the substantia innominata and its changes in Alzheimer disease on MR imaging. METHODS Using a 1.5-T superconductive MR unit, thickness of the substantia innominata was measured on coronal thin-section images obtained in 22 patients with Alzheimer disease and 14 age-matched control subjects. Comparison of these images with postmortem specimens of human brain was also performed. RESULTS On T2-weighted images through the anterior commissure, the substantia innominata was clearly identified between the globus pallidus and the anterior perforated substance. In Alzheimer disease, thinning of the substantia innominata was more frequently observed than in the age-matched controls. CONCLUSIONS Thin-section T2-weighted coronal MR images can demonstrate shrinkage of the substantia innominata, a finding that may aid in the diagnosis of Alzheimer disease.
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
January 2002,
AJNR. American journal of neuroradiology,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
June 1994,
Rinsho shinkeigaku = Clinical neurology,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
April 2007,
Neurobiology of aging,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
April 2005,
Journal of neurology,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
January 1989,
No to shinkei = Brain and nerve,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
January 2003,
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
March 1984,
Neuroscience letters,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
November 1988,
The Journal of comparative neurology,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
May 1985,
No to shinkei = Brain and nerve,
M Sasaki, and
S Ehara, and
Y Tamakawa, and
S Takahashi, and
H Tohgi, and
A Sakai, and
T Mita
January 1967,
Acta biologiae experimentalis,
