-transparent.png){kind=logo}
We previously reported that genes within the major histocompatibility complex influence the intensity of Taenia crassiceps murine cysticercosis. This genetic control, readily apparent in mice of BALB background, was further studied in H-2 congenic and recombinant B10 mice as well as in BALB/c substrains differing in expression of Qa-2 antigens. Similarly low parasite numbers were found in all B10-derived strains infected, regardless of H-2 haplotype, indicating that the effect of H-2 genes in controlling susceptibility is overridden in mice of B10 background. BALB/c substrains differed significantly in susceptibility. BALB/cAnN was highly susceptible, whereas BALB/cJ, in contrast, was highly resistant and BALB/cByJ showed intermediate susceptibility. Susceptibility or resistance in BALB/c substrains may be associated to differences known to distinguish them, such as serum testosterone levels and Qa-2 protein expression. In bidirectional F1 hybrids of C57BL/6J and BALB/cAnN resistance to cysticercosis was inherited as a dominant autosomal trait. In F1 hybrids of BALB/cJ with BALB/cAnN, BALB/cByJ and BALB.K resistance was also inherited as a dominant trait. However, in (BALB/cAnN x BALB/cByJ)F1 and (BALB/cAnN x BALB.K)F1 hybrids, dominant susceptibility to cysticercosis was observed.
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
August 1998,
AIDS (London, England),
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
January 2008,
Retinal cases & brief reports,
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
December 1999,
Parasitology research,
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
January 1989,
Acta Leidensia,
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
November 1989,
Experimental parasitology,
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
January 1991,
Parasitology research,
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
July 1993,
Journal of the American Veterinary Medical Association,
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
January 2013,
Handbook of clinical neurology,
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
December 2009,
The Veterinary record,
G Fragoso, and
E Lamoyi, and
A Mellor, and
C Lomeli, and
T Govezensky, and
E Sciutto
April 1995,
Bulletin de l'Academie nationale de medecine,
