-transparent.png){kind=logo}
In order to analyze systemic immune surveillance in patients with B cell non-Hodgkin's lymphomas (B-NHL), we investigated circulating lymphocytes using two-color flow cytometry. The proportions of CD3-CD56+ natural killer (NK) cells and CD8++(bright) S6F1++ killer-effector T cells corresponding to activated cytotoxic T lymphocytes (aCTL) were studied in the peripheral blood of 26 patients with indolent lymphoma (IL) and 24 with aggressive lymphoma (AL). The AL patients with both limited disease and advanced disease had an increased proportion of NK cells. However, this feature was not evident in IL patients with either limited or advanced disease. In contrast, an increased proportion of aCTL was observed only in IL patients with advanced disease. These findings indicate that IL may differ from AL in terms of immune surveillance against neoplastic B cells.
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
November 2002,
British journal of haematology,
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
January 2005,
Tsitologiia,
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
August 1978,
Clinical and experimental immunology,
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
June 1974,
British journal of haematology,
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
January 1990,
Current topics in microbiology and immunology,
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
January 1978,
Actas dermo-sifiliograficas,
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
March 2004,
Leukemia,
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
July 1993,
Cancer immunology, immunotherapy : CII,
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
April 1990,
Journal of immunology (Baltimore, Md. : 1950),
Y Kuriyama, and
M Nakano, and
Y Kawanishi, and
O Iwase, and
S Aizawa, and
K Toyama
July 1994,
Microscopy research and technique,
