-transparent.png){kind=logo}
In order to determine possible overexpression of cathepsin D and PAI-1 (plasminogen activator inhibitor) in head and neck tumours, cytosols from 92 primary squamous cell carcinomas (SCC), 19 lymph node metastases and 24 adjacent normal tissue samples were examined. For both cathepsin D and PAI-1, significantly elevated concentrations in SCC compared to normal tissue were found, even in pairwise comparison. Moreover, significantly higher cathepsin D and PAI-1 concentration in lymph node metastases than in corresponding normal tissue were also present. The conclusion was drawn that cathepsin D and PAI-1 may play a specific role in the biology of head and neck SCC.
Related Publications
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
January 1992,
European journal of cancer (Oxford, England : 1990),
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
January 2002,
Breast cancer (Tokyo, Japan),
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
January 2000,
The International journal of biological markers,
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
February 1995,
Cancer research,
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
August 1998,
The Laryngoscope,
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
February 2008,
Oral oncology,
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
October 1995,
General & diagnostic pathology,
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
July 2007,
BMC cancer,
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
June 1993,
International journal of oncology,
R Zeillinger, and
S Eder, and
C Schneeberger, and
R Ullrich, and
P Speiser, and
H Swoboda
February 2020,
JNCI cancer spectrum,
