-transparent.png){kind=logo}
In rod photoreceptor cells, Ca2+-bound recoverin associates with disk membranes and inhibits light-dependent phosphorylation of rhodopsin. However, the functional significance of Ca2+-induced membrane association of recoverin has not been fully evaluated. We found that Ca2+-bound recoverin forms a complex with rhodopsin kinase preferentially at the membrane surface. Addition of increasing amounts of membranes promoted the membrane association of recoverin, and remarkably suppressed rhodopsin kinase activity. It was concluded that the Ca2+-recoverin-rhodopsin kinase complex is stabilized by membrane association, leading to effective suppression of the kinase activity.
Related Publications
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
October 1994,
FEBS letters,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
January 2002,
Advances in experimental medicine and biology,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
January 2002,
Advances in experimental medicine and biology,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
October 1995,
The Journal of biological chemistry,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
December 2006,
The Journal of biological chemistry,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
July 2009,
Journal of neurochemistry,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
August 1994,
Biochemical and biophysical research communications,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
January 2000,
Methods in enzymology,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
July 2006,
The Journal of biological chemistry,
K Sanada, and
F Shimizu, and
K Kameyama, and
K Haga, and
T Haga, and
Y Fukada
July 1995,
The Journal of biological chemistry,
