Voiding cystourethrography in female stress incontinence. 1996

R E Pelsang, and W W Bonney
Department of Radiology, The University of Iowa Hospitals and Clinics, Iowa City, 52242-1009, USA.

OBJECTIVE The aims of this study were to determine the sensitivity of voiding cystourethrography (VCUG) in detecting incontinence in women with a history of leakage, the positive and negative predictive values of VCUG for stress incontinence, and how often a history of leakage is accompanied by urethrocele on VCUG and to correlate urethral anatomic measurements with the presence of urethrocele and stress incontinence on VCUG. METHODS A total of 159 women with incontinence or voiding dysfunction were evaluated by VCUG and urodynamic study (UDS). RESULTS VCUG detected stress incontinence in 76% of women with a specific history of stress incontinence. Of 61 women with genuine stress incontinence proven on UDS, only 37 (61%) were identified on VCUG, yielding a positive predictive value of 56%. Twenty-one of 29 women without genuine stress incontinence on UDS but with apparent stress incontinence on VCUG had detrusor instability on UDS, so that urge incontinence was falsely diagnosed as stress incontinence. VCUG had a negative predictive value of 74%. In 40 women with urethroceles, 26 had stress incontinence on VCUG. The anatomic changes in posterior urethrovesical angle, urethral descent, and urethral inclination denote urethroceles but do not correlate with the presence of stress incontinence. CONCLUSIONS In the evaluation of stress incontinence, VCUG is limited because of detrusor instability producing urge incontinence and therefore resulting in false-positive stress incontinence. The anatomic measurements of posterior urethrovesical angle change, urethral descent, and urethral inclination as well as the presence of urethrocele have limited ability in predicting stress incontinence.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D011391 Prolapse The protrusion of an organ or part of an organ into a natural or artificial orifice. Prolapses
D011859 Radiography Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film). Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D001743 Urinary Bladder A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION. Bladder,Bladder Detrusor Muscle,Detrusor Urinae,Bladder Detrusor Muscles,Bladder, Urinary,Detrusor Muscle, Bladder,Detrusor Muscles, Bladder
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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