OBJECTIVE To compare the efficacy of the Unicum, a new ectocervical-endocervical nylon brush, with that of the Cytobrush plus wooden spatula in the collection of cervical-endocervical material. METHODS Thirty-eight patients who underwent routine gynecologic examinations agreed to have a smear taken with the wooden spatula plus Cytobrush and the Unicum. RESULTS The two methods were equally effective in collecting endocervical-ectocervical smears. CONCLUSIONS With our method, sampling is done with only one device; the ectocervix and endocervix are sampled simultaneously, and adequate sampling of the transformation zone must be achieved.