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Abnormalities of chromosomes 1, 3, 16, and 17 were examined in 203 metaphase cells from 12 cases of primary breast carcinoma using fluorescence in situ hybridization with chromosome painting probes. The most common structural abnormalities were chromosomal rearrangements, especially translocations, and chromosome 17 was most frequently involved in these types of changes. Chromosome 16 was preferentially involved in the losses and deletions, while chromosomes 1 and 17 were more involved in the gains, including amplifications, than other chromosomes. This approach has revealed a different profile of abnormalities from those normally shown by G-banding analysis. Some of these changes are likely to be novel and may be biologic or clinical importance in breast cancer.
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
April 1997,
Clinical genetics,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
January 2000,
Pathology, research and practice,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
January 1998,
Pathobiology : journal of immunopathology, molecular and cellular biology,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
March 1995,
American journal of medical genetics,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
June 1999,
Zhonghua yi xue za zhi,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
October 1997,
The American journal of pathology,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
October 1995,
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
June 2001,
Clinica chimica acta; international journal of clinical chemistry,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
June 1993,
Cancer genetics and cytogenetics,
K Anamthawat-Jónsson, and
J E Eyfjörd, and
H M Ogmundsdóttir, and
I Pétursdóttir, and
M Steinarsdóttir
January 1995,
Urologia internationalis,
