Biomaterial Database

Evidence against tailstrings increasing the rate of pelvic inflammatory disease among IUD users. 1996

K L Ebi, and R L Piziali, and M Rosenberg, and H F Wachob

Failure Analysis Associates, Inc., Menlo Park, CA 94025, USA.

A meta-analysis was conducted to determine whether the presence of an IUD tailstring is associated with increased rates of pelvic inflammatory disease among IUD users. Included were seven clinical studies that compared the same IUD with and without a tail, and fifteen clinical studies that compared two similar copper IUDs that differed in the polymer used for the tailstring (polypropylene versus polyethylene). No increase in PID rates was found among users of IUDs with versus without a tail (RR = 1.2, 95% confidence interval 0.6-1.7), or among users of copper IUDs with different tailstring materials (polypropylene vs. polyethylene, RR = 0.9, 95% confidence interval 0.4-1.5). These findings support the hypothesis that the presence of a tailstring does not increase the rate of PID among users of IUDs.

UI	MeSH Term	Description	Entries
D007435	Intrauterine Devices, Copper	Intrauterine contraceptive devices that depend on the release of metallic copper.	Copper Intrauterine Devices,Copper-Releasing IUDs,IUD, Copper Releasing,Copper Intrauterine Device,Copper Releasing IUD,Copper-Releasing IUD,Device, Copper Intrauterine,Devices, Copper Intrauterine,IUD, Copper-Releasing,IUDs, Copper-Releasing,Intrauterine Device, Copper
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011095	Polyethylenes	Synthetic thermoplastics that are tough, flexible, inert, and resistant to chemicals and electrical current. They are often used as biocompatible materials for prostheses and implants.	Ethylene Polymers,Ethene Homopolymers,Homopolymers, Ethene,Polymers, Ethylene
D011126	Polypropylenes	Propylene or propene polymers. Thermoplastics that can be extruded into fibers, films or solid forms. They are used as a copolymer in plastics, especially polyethylene. The fibers are used for fabrics, filters and surgical sutures.	Propene Polymers,Propylene Polymers,Hostalen,Marlex,Marlex Polypropylene,Polypro,Polypropylene,Prolene,Polymers, Propene,Polymers, Propylene,Polypropylene, Marlex
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D004867	Equipment Design	Methods and patterns of fabricating machines and related hardware.	Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000292	Pelvic Inflammatory Disease	A spectrum of inflammation involving the female upper genital tract and the supporting tissues. It is usually caused by an ascending infection of organisms from the endocervix. Infection may be confined to the uterus (ENDOMETRITIS), the FALLOPIAN TUBES; (SALPINGITIS); the ovaries (OOPHORITIS), the supporting ligaments (PARAMETRITIS), or may involve several of the above uterine appendages. Such inflammation can lead to functional impairment and infertility.	Adnexitis,Inflammatory Disease, Pelvic,Inflammatory Pelvic Disease,Pelvic Disease, Inflammatory,Disease, Inflammatory Pelvic,Disease, Pelvic Inflammatory,Diseases, Inflammatory Pelvic,Diseases, Pelvic Inflammatory,Inflammatory Diseases, Pelvic,Inflammatory Pelvic Diseases,Pelvic Diseases, Inflammatory,Pelvic Inflammatory Diseases
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths