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The giant hemoglobin, which occurs in free solution in the blood of earthworms, contains copper and zinc and exhibits superoxide dismutase activity as assessed by competition assays using cytochrome c or nitroblue tetrazolium. On a molar basis, the activity of this hemoglobin was approximately 10% that of the mammalian copper, zinc superoxide dismutase. The dodecamer, which contains the globin chains but lacks the linker subunits, had very little activity when compared to the complete native molecule. This suggests that the superoxide dismutase activity resides in one of the linker subunits. This is the first report of a superoxide dismutase bound to a respiratory pigment.
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
June 2014,
Biochimica et biophysica acta,
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
December 1988,
Proceedings of the National Academy of Sciences of the United States of America,
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
February 1965,
Comparative biochemistry and physiology,
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
December 1962,
The American journal of psychology,
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
February 1992,
Lipids,
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
June 1993,
The Journal of biological chemistry,
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
January 1961,
Proceedings of the Koninklijke Nederlandse Akademie van Wetenschappen. Series C. Biological and medical sciences,
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
December 1981,
Journal of ultrastructure research,
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
August 1968,
Science (New York, N.Y.),
S I Liochev, and
A R Kuchumov, and
S N Vinogradov, and
I Fridovich
January 1993,
Biochemistry and cell biology = Biochimie et biologie cellulaire,
