Biomaterial Database

[A new case of chronic progressive bulbo-pontine paralysis and deafness]. 1977

J E Van Laere

The author reports a new case of chronic progressive bulbo-pontine paralysis with deafness. This case differed from other cases previously published on the basis of the later age of onset of labio-glosso-laryn-geal paralysis, by the absence of any vestibular changes despite bilateral involvement of the acoustic centres and above all by the normality of deep tendon reflexes. The author feels that chronic progressive vulvo-pontine paralysis with deafness is a specific individual condition, worthy of consideration as an autonomic clinical entity.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010244	Bulbar Palsy, Progressive	A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)	Fazio-Londe Disease,Fazio-Londe Syndrome,Fazio-Londe's Disease,Fazio-Londe's Syndrome,Paralysis, Bulbar,Bulbar Palsy,Bulbar Palsy, Progressive, Of Childhood,Childhood Progressive Bulbar Palsy,Progressive Bulbar Palsy of Childhood,Bulbar Palsies,Bulbar Palsies, Progressive,Bulbar Paralyses,Bulbar Paralysis,Disease, Fazio-Londe,Disease, Fazio-Londe's,Fazio Londe Disease,Fazio Londe Syndrome,Fazio Londe's Disease,Fazio Londe's Syndrome,Palsies, Bulbar,Palsies, Progressive Bulbar,Palsy, Bulbar,Palsy, Progressive Bulbar,Progressive Bulbar Palsies,Syndrome, Fazio-Londe,Syndrome, Fazio-Londe's
D003638	Deafness	A general term for the complete loss of the ability to hear from both ears.	Deafness Permanent,Hearing Loss Permanent,Prelingual Deafness,Deaf Mutism,Deaf-Mutism,Deafness, Acquired,Hearing Loss, Complete,Hearing Loss, Extreme,Acquired Deafness,Complete Hearing Loss,Deafness, Prelingual,Extreme Hearing Loss,Permanent, Deafness,Permanent, Hearing Loss,Permanents, Deafness
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000367	Age Factors	Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.	Age Reporting,Age Factor,Factor, Age,Factors, Age
D013577	Syndrome	A characteristic symptom complex.	Symptom Cluster,Cluster, Symptom,Clusters, Symptom,Symptom Clusters,Syndromes