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Budd-Chiari syndrome attributed to protein C deficiency. 1996
S Sugano, and
T Suzuki, and
H Makino, and
S Yanagimoto, and
M Nishio, and
H Onmura, and
M Iinuma, and
T Matuda, and
Y Shinozawa
Department of Internal Medicine, Gastroenterology/Hepatology Division, Saiseikai Wakakusa Hospital, Yokohama, Japan.
The protein C anticoagulant pathway is an important downregulating mechanism of the blood coagulation cascade. We report a 47-yr-old male with Budd-Chiari syndrome and occlusion of the inferior vena cava. His plasma protein C antigen level was decreased to 42%, and its activity was 34%. Other coagulable factors were normal. Protein C deficiency should be considered a possible etiological factor of the Budd-Chiari syndrome.
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