BIOMAT Database Logo BIOMAT Database Logo

Occurrence of nitro and non-nitro benzenoid musk compounds in human adipose tissue. 1996

S Müller, and P Schmid, and C Schlatter
Institute of Toxicology, Swiss Federal Institute of Technology, Schwerzenbach, Switzerland.

Nitro benzenoid musk compounds (Musk tibetene [CAS no. 145-39-1], Musk ambrette [83-66-9], Musk moskene [116-66-5], Musk ketone [81-14-1] and Musk xylene [81-15-2]) and non-nitro benzenoid musks (Celestolide [13171-00-1], Galaxolide [1222-05-5]) and Fixolide [1506-02-1] [21445-77-7] were analysed in 15 human adipose tissue samples from Switzerland by gas chromatography/high resolution mass spectrometry. The levels of Musk xylene and Galaxolide ranged up to 288 ng/g lipids and 171 ng/g lipids, respectively. The concentrations of non-nitro benzenoid musks found in human adipose tissue raise concern since very few toxicological data are available.

UI MeSH Term Description Entries
D007189 Indans Aryl CYCLOPENTANES that are a reduced (protonated) form of INDENES. Indanones
D008055 Lipids A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed) Lipid
D008297 Male Males
D008401 Gas Chromatography-Mass Spectrometry A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds. Chromatography, Gas-Liquid-Mass Spectrometry,Chromatography, Gas-Mass Spectrometry,GCMS,Spectrometry, Mass-Gas Chromatography,Spectrum Analysis, Mass-Gas Chromatography,Gas-Liquid Chromatography-Mass Spectrometry,Mass Spectrometry-Gas Chromatography,Chromatography, Gas Liquid Mass Spectrometry,Chromatography, Gas Mass Spectrometry,Chromatography, Mass Spectrometry-Gas,Chromatography-Mass Spectrometry, Gas,Chromatography-Mass Spectrometry, Gas-Liquid,Gas Chromatography Mass Spectrometry,Gas Liquid Chromatography Mass Spectrometry,Mass Spectrometry Gas Chromatography,Spectrometries, Mass-Gas Chromatography,Spectrometry, Gas Chromatography-Mass,Spectrometry, Gas-Liquid Chromatography-Mass,Spectrometry, Mass Gas Chromatography,Spectrometry-Gas Chromatography, Mass,Spectrum Analysis, Mass Gas Chromatography
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009153 Mutagens Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. Clastogen,Clastogens,Genotoxin,Genotoxins,Mutagen
D010476 Perfume A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell, especially a fluid containing fragrant natural oils extracted from flowers, woods, etc., or similar synthetic oils. (Random House Unabridged Dictionary, 2d ed)
D002102 Cadaver A dead body, usually a human body. Corpse,Cadavers,Corpses
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D002850 Chromatography, Gel Chromatography on non-ionic gels without regard to the mechanism of solute discrimination. Chromatography, Exclusion,Chromatography, Gel Permeation,Chromatography, Molecular Sieve,Gel Filtration,Gel Filtration Chromatography,Chromatography, Size Exclusion,Exclusion Chromatography,Gel Chromatography,Gel Permeation Chromatography,Molecular Sieve Chromatography,Chromatography, Gel Filtration,Exclusion Chromatography, Size,Filtration Chromatography, Gel,Filtration, Gel,Sieve Chromatography, Molecular,Size Exclusion Chromatography

Related Publications

S Müller, and P Schmid, and C Schlatter
[Nitro-musk compounds in breast milk].
October 1993, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)),
S Müller, and P Schmid, and C Schlatter
Polycyclic musk fragrances in human adipose tissue and human milk.
November 1996, Chemosphere,
S Müller, and P Schmid, and C Schlatter
Occurrence of synthetic polycyclic and nitro musk compounds in sewage sludge from municipal wastewater treatment plants.
December 2021, The Science of the total environment,
S Müller, and P Schmid, and C Schlatter
[Occurrence of hexachlorobenzene and polychlorobiphenyl compounds from chlorinated insecticides in human adipose tissue and human milk].
January 1972, Die Nahrung,
S Müller, and P Schmid, and C Schlatter
[Mutagenicity, genotoxicity and cogenotoxicity of environmentally relevant nitro musk compounds].
May 1996, Zentralblatt fur Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine,
S Müller, and P Schmid, and C Schlatter
Occurrence and accumulation patterns of polycyclic aromatic hydrocarbons and synthetic musk compounds in adipose tissues of Korean females.
February 2012, Chemosphere,
S Müller, and P Schmid, and C Schlatter
Synthetic Musk Compounds in Human Biological Matrices: Analytical Methods and Occurrence-A Review.
May 2021, Journal of AOAC International,
S Müller, and P Schmid, and C Schlatter
Non-alternant non-benzenoid aromatic compounds: past, present, and future.
February 2015, Chemical record (New York, N.Y.),
S Müller, and P Schmid, and C Schlatter
Occurrence and fate of synthetic musk compounds in water environment.
January 2010, Water research,
S Müller, and P Schmid, and C Schlatter
Steric and energetic characterizations of mouse and human musk receptors activated by nitro musk smelling compounds at molecular level: Statistical physics treatment and molecular docking analysis.
October 2021, International journal of biological macromolecules,
Copied contents to your clipboard!