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The sensitivities and specificities of enzyme immunoassay (EIA) kits for the detection of antibodies to hepatitis C virus (HCV) were compared in donor blood screening. A total of 3308 donors were examined using Akvapast immunodiagnosticum (St. Petersburg), lot 12. Anti-HCV antibodies were detected in 43 (1.3%) subjects. Blood sera of these donors were additionally investigated using other lots of Akvapast, Hepascan (Bioservice, Moscow), Blot-0.5 (Bioservice, Moscow), and immunoComb (France). The studies demonstrated that none of the agents used can be acknowledged as ideally sensitive and specific for the detection of anti-HCV antibodies. Maximally sensitive diagnostic kits should be preferred for the screening of donors of blood components and for other mass surveys. Highly-specific test systems are advisable for profound examinations and diagnostic monitoring. The creation of a system of reference and expert diagnosis of hepatitis C remains a pressing task.
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
January 2004,
Voprosy virusologii,
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
January 1991,
Voprosy virusologii,
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
October 1958,
The Cornell veterinarian,
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
January 1998,
Voprosy virusologii,
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
January 1989,
Voprosy virusologii,
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
May 1981,
Tropical animal health and production,
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
May 1968,
American journal of clinical pathology,
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
May 1993,
Gastroenterologia Japonica,
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
August 1989,
Lancet (London, England),
E B Zhiburt, and
N V Bel'gesov, and
V V Danil'chenko, and
N B Serebrianaia, and
V K Potepun, and
S V Sidorkevich, and
V B Vasiliuk, and
K Iu Zhuravlev
May 2002,
Journal of clinical microbiology,
