Biomaterial Database

Submassive necrosis of liver of Channa gachua, a fresh water fish during experimental alloxan diabetes. 1977

K A Goel

An extensive change in the liver architecture leading to submassive necrosis has been observed in Channa gachua toxicated with alloxan. An intramuscular dosage of 10 mg/kg of the toxicant mobilized liver glycogen after 4 h of application leading to hyperglycaemia of blood. The serial changes occurring in the liver have been discussed at intervals of 24, 48, 96 and 100 h, when the fish reached to comasate condition and finally died.

UI	MeSH Term	Description	Entries
D008107	Liver Diseases	Pathological processes of the LIVER.	Liver Dysfunction,Disease, Liver,Diseases, Liver,Dysfunction, Liver,Dysfunctions, Liver,Liver Disease,Liver Dysfunctions
D009336	Necrosis	The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D003921	Diabetes Mellitus, Experimental	Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.	Alloxan Diabetes,Streptozocin Diabetes,Streptozotocin Diabetes,Experimental Diabetes Mellitus,Diabete, Streptozocin,Diabetes, Alloxan,Diabetes, Streptozocin,Diabetes, Streptozotocin,Streptozocin Diabete
D005399	Fishes	A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia