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A single pessary containing 0-5 mg 16, 16 dimethyl prostaglandin E2 p-benzaldehyde semicarbazone ester was used for cervical dilatation prior to vacuum aspiration in 124 first trimester nulliparae. Five hours after prostaglandin administration the cervix had dilated to 8 mm or more in 87 patients (70 per cent). The uterus was evacuated in these patients without mechanical dilatation of the cervix. In the remaining 37 patients the cervix had become soft and dilated 5 to 7 mm and further mechanical dilatation could be carried out easily. Side effects were minor and included vomiting in two patients, diarrhoea in one and transient pyrexia in two patients. There were no complications and no damage to the cervix or uterus during evacuation.
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
August 1975,
Prostaglandins,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
April 1983,
Contraception,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
June 1985,
The Journal of the Florida Medical Association,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
April 1998,
British journal of obstetrics and gynaecology,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
January 1988,
Journal of obstetrics and gynaecology,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
September 1982,
Asia-Oceania journal of obstetrics and gynaecology,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
October 1982,
British journal of obstetrics and gynaecology,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
January 1983,
Advances in prostaglandin, thromboxane, and leukotriene research,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
September 1973,
Prostaglandins,
S M Karim, and
S S Ratnam, and
R N Prasad, and
Y M Wong
July 1988,
Human reproduction (Oxford, England),
