Histone 5 from carp erythrocytes. 1977

B L Miki, and J M Neelin

Histone 5 (H5) has been isolated from carp (Cyprinus carpio) erythrocytes and identified by its amino acid composition. It was found in very small relative amounts, despite the use of either 50 mM sodium bisulfite or 1.0 mM phenylmethylsulfonyl fluoride to inhibit endogenous protease activity. Carp H5 differed significantly from H5's of other lower vertebrates in its amino acid composition, position of elution from Amberlite CG-50 ion-exchange columns, and its unusually high electrophoretic mobility. The extensive quantitative and qualtitative variability of H5 from different species must be reconciled with the presumed functional homology of these cells.

UI MeSH Term Description Entries
D008970 Molecular Weight The sum of the weight of all the atoms in a molecule. Molecular Weights,Weight, Molecular,Weights, Molecular
D002347 Carps Common name for a number of different species of fish in the family Cyprinidae. This includes, among others, the common carp, crucian carp, grass carp, and silver carp. Carassius carassius,Crucian Carp,Cyprinus,Grass Carp,Carp,Ctenopharyngodon idellus,Cyprinus carpio,Hypophthalmichthys molitrix,Koi Carp,Silver Carp,Carp, Crucian,Carp, Grass,Carp, Koi,Carp, Silver,Carps, Crucian,Carps, Grass,Carps, Silver,Crucian Carps,Grass Carps,Silver Carps
D003530 Cyprinidae A family of freshwater fish comprising the minnows or CARPS. Barbels,Chub,Dace,Minnows,Roach (Fish),Shiner,Tench,Tinca,Barbus,Rutilus rutilus,Tinca tinca,Chubs,Shiners,Tinca tincas,tinca, Tinca
D004912 Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN. Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D006657 Histones Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each. Histone,Histone H1,Histone H1(s),Histone H2a,Histone H2b,Histone H3,Histone H3.3,Histone H4,Histone H5,Histone H7
D000596 Amino Acids Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins. Amino Acid,Acid, Amino,Acids, Amino
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

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