-transparent.png){kind=logo}
A specific radioimmunoassay has been developed for measuring oestriol-16alpha glucuronide in pregnancy plasma using a highly specific antiserum. The specificity of this antiserum has been assessed by the 50% displacement method and by measuring oestriol-16alpha-glucuronide concentrations in pregnancy plasma samples, both with and without chromatography. The antiserum was found to have Ka of 1.3 X 10(10) M-1. The assay had a sensitivity of 5 pg (least quantity of oestriol-16alpha-glucuronide distinguishable from the zero point, p less than 0.05), an intra-assay variation of 6.07% and an inter-assay variation of 3.36%. The assay was used to measure plasma oestriol-16alpha-glucuronide concentrations throughout eight pregnancies, five of which were normal and three had some defined abnormality.
E J Kerr, and
B K Park, and
P D Dean
July 1973,
Clinica chimica acta; international journal of clinical chemistry,
E J Kerr, and
B K Park, and
P D Dean
February 1976,
Journal of steroid biochemistry,
E J Kerr, and
B K Park, and
P D Dean
November 1973,
Journal of steroid biochemistry,
E J Kerr, and
B K Park, and
P D Dean
January 1977,
Journal of steroid biochemistry,
E J Kerr, and
B K Park, and
P D Dean
June 1976,
Journal of clinical pathology,
E J Kerr, and
B K Park, and
P D Dean
October 1983,
Chemical & pharmaceutical bulletin,
E J Kerr, and
B K Park, and
P D Dean
July 1976,
American journal of obstetrics and gynecology,
E J Kerr, and
B K Park, and
P D Dean
May 1995,
Annals of clinical biochemistry,
E J Kerr, and
B K Park, and
P D Dean
April 1971,
The Journal of obstetrics and gynaecology of the British Commonwealth,
E J Kerr, and
B K Park, and
P D Dean
August 1977,
American journal of obstetrics and gynecology,
