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Tonography of the eye was performed in 15 patients with proven myasthenia gravis and ten control subjects, before and after administration of edrophonium (Tensilon). In nine myasthenics there was definite intra-ocular pressure rise after an average of 20 seconds. In control subjects a comparable pressure rise did not occur. Tonography was superior to results obtained with serial stimulation of the ulnar nerve. The results confirm that tonography of the eye is a valuable and reliable diagnostic test of myasthenia gravis.
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