-transparent.png){kind=logo}
A fixed-interval schedule of food presentation was used to study the effects of apomorphine, ET-495 and clonidine and interactions between these drugs and naloxone in the rat. The rate of responding under this schedule was decreased by low doses of apomorphine (0.03--0.3 mg/kg), ET-495 (0.3-1.0 mg/kg) and clonidine (0.03--0.3 mg/kg). Naloxone, at a dose (3 mg/kg) which did not itself alter responding, potentiated the rate decreasing effects of apomorphine and ET-495 but did not alter the effects of clonidine. It is suggested that the rate decreasing effects of low doses of apomorphine and ET-495 may be related to presynaptic inhibition of dopamine neurons and that under certain circumstances naloxone may also inhibit dopaminergic activity.
R A Harris, and
D Snell, and
H H Loh, and
E L Way
January 1991,
Psychopharmacology,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
January 2002,
The Journal of pharmacology and experimental therapeutics,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
January 1986,
Psychopharmacology bulletin,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
February 1995,
Drug and alcohol dependence,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
January 1978,
Communications in psychopharmacology,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
April 2006,
The Journal of neuroscience : the official journal of the Society for Neuroscience,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
January 1979,
Progress in neuro-psychopharmacology,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
November 1994,
The Journal of pharmacology and experimental therapeutics,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
May 1990,
Brain research bulletin,
R A Harris, and
D Snell, and
H H Loh, and
E L Way
March 2016,
Journal of behavioral addictions,
