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Seventeen insulin dependent diabetics were studied after two to four weeks of insulin treatment in a situation approximating to their normal daily life. Some endogenous insulin secretion, assessed by plasma C-peptide determinations, was present in all. Plasma C-peptide concentration was positively correlated with the blood glucose concentration and increased after breakfast, lunch and dinner (p less than 0.01); both peak values and relative increases were lower than those observed in normal subjects (p less than 0.01). The highest insulin secretory capacity was found in subjects with the least unstable blood glucose concentration (r=0.57, p less than 0.03), and these patients required the smallest insulin doses (r=0.54, P less than 0.04). These findings demonstrate the metabolic importance of a preserved B-cell function.
O K Faber, and
C Binder
January 1985,
Behaviour research and therapy,
O K Faber, and
C Binder
January 1979,
Hormone and metabolic research. Supplement series,
O K Faber, and
C Binder
January 1979,
Medical journal of Zambia,
O K Faber, and
C Binder
January 1981,
Acta medica Scandinavica. Supplementum,
O K Faber, and
C Binder
July 1983,
Behavior modification,
O K Faber, and
C Binder
April 1988,
Casopis lekaru ceskych,
O K Faber, and
C Binder
December 1983,
The Tohoku journal of experimental medicine,
O K Faber, and
C Binder
December 1981,
Psychosomatic medicine,
O K Faber, and
C Binder
January 1992,
Minerva endocrinologica,
O K Faber, and
C Binder
January 1986,
Acta diabetologica latina,
