Protein-losing gastropathy associated with cytomegalovirus: a rare and late complication of allogeneic bone marrow transplantation. 1996

C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
Bone Marrow Transplantation Unit, Institut Gustave Roussy, Villejuif, France.

A 36-year-old women with chronic myelogenous leukemia in first chronic phase received a bone marrow transplant from her HLA-identical brother. The preparatory regimen consisted of total body irradiation (10 Gy) and cyclophosphamide (60 mg/kg for 2 days). Full engraftment was achieved and the woman was monitored as an outpatient after discharge from hospital on day 35. One year after BMT, while she was on cyclosporin A and steroids because of chronic graft-versus-host disease, the patient developed protein-losing gastropathy associated with cytomegalovirus infection (with no gastrointestinal symptoms), which regressed spontaneously in 4 weeks.

UI MeSH Term Description Entries
D008297 Male Males
D011504 Protein-Losing Enteropathies Pathological conditions in the INTESTINES that are characterized by the gastrointestinal loss of serum proteins, including SERUM ALBUMIN; IMMUNOGLOBULINS; and at times LYMPHOCYTES. Severe condition can result in HYPOGAMMAGLOBULINEMIA or LYMPHOPENIA. Protein-losing enteropathies are associated with a number of diseases including INTESTINAL LYMPHANGIECTASIS; WHIPPLE'S DISEASE; and NEOPLASMS of the SMALL INTESTINE. Enteropathy, Exudative,Idiopathic Hypercatabolic Hypoproteinemia,Enteropathy, Protein-Losing,Protein-Losing Enteropathy,Enteropathies, Exudative,Enteropathies, Protein-Losing,Exudative Enteropathies,Exudative Enteropathy,Hypercatabolic Hypoproteinemia, Idiopathic,Hypercatabolic Hypoproteinemias, Idiopathic,Hypoproteinemia, Idiopathic Hypercatabolic,Hypoproteinemias, Idiopathic Hypercatabolic,Idiopathic Hypercatabolic Hypoproteinemias,Protein Losing Enteropathies,Protein Losing Enteropathy
D003586 Cytomegalovirus Infections Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults. CMV Inclusion,CMV Inclusions,Congenital CMV Infection,Congenital Cytomegalovirus Infection,Cytomegalic Inclusion Disease,Cytomegalovirus Colitis,Cytomegalovirus Inclusion,Cytomegalovirus Inclusion Disease,Cytomegalovirus Inclusions,Inclusion Disease,Perinatal CMV Infection,Perinatal Cytomegalovirus Infection,Renal Tubular Cytomegalovirus Inclusion,Renal Tubular Cytomegalovirus Inclusions,Salivary Gland Virus Disease,Severe Cytomegalovirus Infection,Severe Cytomegalovirus Infections,Infections, Cytomegalovirus,CMV Infection, Congenital,CMV Infection, Perinatal,Colitis, Cytomegalovirus,Congenital CMV Infections,Congenital Cytomegalovirus Infections,Cytomegalic Inclusion Diseases,Cytomegalovirus Colitides,Cytomegalovirus Inclusion Diseases,Cytomegalovirus Infection,Cytomegalovirus Infection, Congenital,Cytomegalovirus Infection, Perinatal,Cytomegalovirus Infection, Severe,Cytomegalovirus Infections, Severe,Disease, Cytomegalic Inclusion,Disease, Cytomegalovirus Inclusion,Diseases, Cytomegalovirus Inclusion,Inclusion Disease, Cytomegalic,Inclusion Disease, Cytomegalovirus,Inclusion Diseases,Inclusion Diseases, Cytomegalovirus,Inclusion, CMV,Inclusion, Cytomegalovirus,Infection, Congenital CMV,Infection, Congenital Cytomegalovirus,Infection, Cytomegalovirus,Infection, Perinatal CMV,Infection, Perinatal Cytomegalovirus,Infection, Severe Cytomegalovirus,Perinatal CMV Infections,Perinatal Cytomegalovirus Infections
D005260 Female Females
D005758 Gastritis, Hypertrophic GASTRITIS with HYPERTROPHY of the GASTRIC MUCOSA. It is characterized by giant gastric folds, diminished acid secretion, excessive MUCUS secretion, and HYPOPROTEINEMIA. Symptoms include VOMITING; DIARRHEA; and WEIGHT LOSS. Menetrier Disease,Gastritis, Familial Giant Hypertrophic,Giant Hypertrophic Gastritis,Menetrier's Disease,Disease, Menetrier,Disease, Menetrier's,Gastritis, Giant Hypertrophic,Hypertrophic Gastritis,Hypertrophic Gastritis, Giant,Menetriers Disease
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D014184 Transplantation, Homologous Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals. Transplantation, Allogeneic,Allogeneic Grafting,Allogeneic Transplantation,Allografting,Homografting,Homologous Transplantation,Grafting, Allogeneic
D015466 Leukemia, Myeloid, Chronic-Phase The initial phase of chronic myeloid leukemia consisting of an relatively indolent period lasting from 4 to 7 years. Patients range from asymptomatic to those exhibiting ANEMIA; SPLENOMEGALY; and increased cell turnover. There are 5% or fewer blast cells in the blood and bone marrow in this phase. Granulocytic Leukemia, Chronic, Stable-Phase,Leukemia, Granulocytic, Chronic-Phase,Leukemia, Myelogenous, Chronic-Phase,Leukemia, Myeloid, Stable-Phase,Myelogenous Leukemia, Chronic, Chronic-Phase,Myeloid Leukemia, Chronic, Chronic-Phase,Myeloid Leukemia, Chronic, Stable-Phase,Granulocytic Leukemia, Chronic, Stable Phase,Leukemia, Granulocytic, Chronic Phase,Leukemia, Myelogenous, Chronic Phase,Leukemia, Myeloid, Chronic Phase,Leukemia, Myeloid, Stable Phase,Myelogenous Leukemia, Chronic, Chronic Phase,Myeloid Leukemia, Chronic, Chronic Phase

Related Publications

C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
February 1992, Bone marrow transplantation,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
October 1994, Bone marrow transplantation,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
January 1994, Haematologica,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
November 2008, European journal of pediatrics,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
January 1994, Gastroenterologie clinique et biologique,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
June 2012, BMJ case reports,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
April 2004, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
May 2016, Gastroenterology,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
April 2023, La Revue de medecine interne,
C Pinho Vaz, and A Ibrahim, and A Avila Garavito, and J M Vantelon, and J H Bourhis, and I Charnoze, and C Buffet, and J L Pico
January 2006, La Pediatria medica e chirurgica : Medical and surgical pediatrics,
Copied contents to your clipboard!