-transparent.png){kind=logo}
The diffusion of Fucidin, gentamicin, and clindamycin from acrylic cement was tested in an in vitro system. The activity of Fucidin was very short-lived and only against gram-positive organisms; gentamicin inhibited gram-positive and gram-negative organisms for twenty-two and eleven days respectively; clindamycin had significant action only against gram-positive organisms and retained some activity for fifty-six days. We suggest that the destruction of organisms in the tissues is more likely to be achieved by topical and intravenous administration of antibiotics during the operation than by incorporation of antibiotic in the cement.
Related Publications
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
September 1978,
Journal of biomedical materials research,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
February 1986,
The Journal of antimicrobial chemotherapy,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
August 1977,
The Journal of bone and joint surgery. British volume,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
June 1999,
Clinical orthopaedics and related research,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
November 1978,
Journal of biomedical materials research,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
November 1989,
The Journal of bone and joint surgery. British volume,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
December 1988,
The Journal of bone and joint surgery. American volume,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
January 1993,
Cancer treatment and research,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
January 1984,
Chirurgia narzadow ruchu i ortopedia polska,
J Hill, and
L Klenerman, and
S Trustey, and
R Blowers
February 1994,
The Journal of antimicrobial chemotherapy,
