-transparent.png){kind=logo}
A case of a 5-year-old girl is described whose clinical features included postnatal growth retardation, microcephaly and characteristic facial appearance. These are recognized as the main features of the Dubowitz syndrome. Apart from these features, our patient had recurrent infections of the sinopulmonary tract, high serum IgE levels, defective chemotaxis of polymorphonuclear cells and defective antibody response, findings characterizing the hyper-IgE syndrome. The co-existence of these two syndromes is rare and we suggest that this is the first such case in the literature. CONCLUSIONS Patients with the Dubowitz syndrome will Dubowitz syndrome will require long-term follow up because there is a considerable risk for the syndrome to co-exist with primary immunodeficiency or for malignancies to develop.
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
February 2005,
Immunological reviews,
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
January 1989,
Current problems in dermatology,
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
June 2017,
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery,
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
January 2024,
Current pediatric reviews,
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
May 2008,
International journal of pediatric otorhinolaryngology,
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
January 2001,
The Journal of clinical pediatric dentistry,
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
January 1990,
The Turkish journal of pediatrics,
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
February 2024,
Annals of medicine and surgery (2012),
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
May 2008,
Immunology and allergy clinics of North America,
K Antoniades, and
M Hatzistilianou, and
G Pitsavas, and
C Agouridaki, and
F Athanassiadou
January 2022,
Frontiers in medicine,
