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Rats fed a vitamin E-deficient diet containing 10% "stripped" corn oil had reduced growth rate and elevated platelet count by 12 weeks of age, and a normocytic anemia with elevated reticulocytes by 16 weeks of age. After 5 months, rats became emaciated and developed kyphoscoliosis. Some rats developed skin ulcers and tremors, and mortality was high. Neuromuscular lesions included a chronic necrotizing myopathy and localized axonal dystrophy. There was also a selective activation of lysosomes in the central nervous system microcirculation. Liver ascorbic acid of deficient rats was the same as in those receiving vitamin E. Urinary excretion of p-hydroxyphenylpyruvate after a tyrosine load was also the same in deficient and control rats. It was concluded that neither vitamin C synthesis or utilization was affected the E-deficient rats.
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
November 1939,
The Journal of hygiene,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
July 1989,
The British journal of dermatology,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
August 1953,
The Journal of physiology,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
April 1985,
Nippon Ganka Gakkai zasshi,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
August 1936,
The Journal of physiology,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
January 1981,
Acta neuropathologica,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
March 1962,
The American journal of physiology,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
October 1970,
Helvetica odontologica acta,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
September 1940,
The Biochemical journal,
L J Machlin, and
R Filipski, and
J Nelson, and
L R Horn, and
M Brin
January 1943,
The Biochemical journal,
