Biomaterial Database

Quantitative high-pressure liquid chromatographic determination of thimerosal in pharmaceutical formulations. 1977

C C Fu, and M J Sibley

A quantitative high-pressure liquid chromatographic method an anion-exchange resin column and an aqueous perchlorate solution as the mobile phase is employed for the determination of thimerosal in pharmaceutical formulations. With a liquid formulation containing large amounts of edetate disodium, calcium chloride is used for complexation to eliminate the interference from edetate disodium.

UI	MeSH Term	Description	Entries
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D002851	Chromatography, High Pressure Liquid	Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.	Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D003124	Colorimetry	Any technique by which an unknown color is evaluated in terms of standard colors. The technique may be visual, photoelectric, or indirect by means of spectrophotometry. It is used in chemistry and physics. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
D005035	Ethylmercury Compounds	Organic mercury compounds in which the mercury is attached to an ethyl group.	Ethyl Mercury Compounds,Ethylmercurials,Compounds, Ethyl Mercury,Compounds, Ethylmercury,Mercury Compounds, Ethyl
D013849	Thimerosal	An ethylmercury-sulfidobenzoate that has been used as a preservative in VACCINES; ANTIVENINS; and OINTMENTS. It was formerly used as a topical antiseptic. It degrades to ethylmercury and thiosalicylate.	Mercurothiolate,Thiomersal,Thiomersalate,Merthiolate,Sodium Ethylmercurithiosalicylate,Vitaseptol,Ethylmercurithiosalicylate, Sodium