Biomaterial Database

Orofacial lesions in Crohn's disease. 1996

S Misra, and M E Ament

Division of Pediatric Gastroenterology and Nutrition, UCLA Medical Center, USA.

We describe a female patient with Crohn's disease who presented with longstanding gingival swelling. She went into remission after surgery, but had labial involvement while in remission. A review of the literature is presented with special reference to the clinical characteristics of orofacial Crohn's disease and Melkersson-Rosenthal syndrome, which can mimic such presentation of Crohn's disease.

UI	MeSH Term	Description	Entries
D008047	Lip Diseases	Diseases involving the LIP.	Disease, Lip,Diseases, Lip,Lip Disease
D008556	Melkersson-Rosenthal Syndrome	An idiopathic syndrome characterized by one or more of the following; recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue (lingua plicata). The onset is usually in childhood and relapses are common. Cheilitis granulomatosa is a monosymptomatic variant of this condition. (Dermatol Clin 1996 Apr;14(2):371-9; Magalini & Magalini, Dictionary of Medical Syndromes, 4th ed, p531)	Cheilitis Granulomatosa, Facial Neuropathy, Orofacial Edema,Granulomatous Cheilitis,Cheilitis Granulomatosa,Cheilitis Granulomatosa, Orofacial Edema, Facial Neuropathy,Facial Neuropathy, Cheilitis Granulomatosa, Orofacial Edema,Facial Neuropathy, Orofacial Edema, Cheilitis Granulomatosa,Macrocheilia, Facial Palsy, Edema,Melkerson-Rosenthal Syndrome,Melkersson Syndrome,Melkersson-Rosenthal-Miescher Syndrome,Miescher-Melkersson-Rosenthal Granulomatous Cheilitis,Orofacial Edema, Cheilitis Granulomatosa, Facial Neuropathy,Orofacial Edema, Facial Neuropathy, Cheilitis Granulomatosa,Rosenthal-Melkerson Syndrome,Rosenthal-Melkersson Syndrome,Syndrome, Melkerson Rosenthal,Cheilitis, Miescher-Melkersson-Rosenthal Granulomatous,Granulomatous Cheilitis, Miescher-Melkersson-Rosenthal,Melkerson Rosenthal Syndrome,Melkersson Rosenthal Miescher Syndrome,Melkersson Rosenthal Syndrome,Miescher Melkersson Rosenthal Granulomatous Cheilitis,Rosenthal Melkerson Syndrome,Rosenthal Melkersson Syndrome
D003424	Crohn Disease	A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.	Colitis, Granulomatous,Enteritis, Granulomatous,Enteritis, Regional,Ileitis, Regional,Ileitis, Terminal,Ileocolitis,Crohn's Disease,Crohn's Enteritis,Inflammatory Bowel Disease 1,Regional Enteritis,Crohns Disease,Granulomatous Colitis,Granulomatous Enteritis,Regional Ileitides,Regional Ileitis,Terminal Ileitis
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260	Female		Females
D005882	Gingival Diseases	Diseases involving the GINGIVA.	Epulis,Gingivosis,Epulides,Disease, Gingival,Diseases, Gingival,Gingival Disease,Gingivoses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults

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